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Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics

The reduced development of COVID-19 for children compared to adults provides some tantalizing clues on the pathogenesis and transmissibility of this pandemic virus. First, ACE2, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor, is reduced in the respiratory tract in children...

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Detalles Bibliográficos
Autores principales: Steinman, Jonathan Baruch, Lum, Fok Moon, Ho, Peggy Pui-Kay, Kaminski, Naftali, Steinman, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547272/
https://www.ncbi.nlm.nih.gov/pubmed/32883878
http://dx.doi.org/10.1073/pnas.2012358117