P2Y(2) Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

Leishmaniasis is a neglected tropical disease caused by an intracellular parasite of the genus Leishmania. Damage-associated molecular patterns (DAMPs) such as UTP and ATP are released from infected cells and, once in the extracellular medium, activate P2 purinergic receptors. P2Y(2) and P2X7 recept...

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Detalles Bibliográficos
Autores principales: Thorstenberg, Maria Luiza, Martins, Monique Daiane Andrade, Figliuolo, Vanessa, Silva, Claudia Lucia Martins, Savio, Luiz Eduardo Baggio, Coutinho-Silva, Robson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547346/
https://www.ncbi.nlm.nih.gov/pubmed/33061823
http://dx.doi.org/10.1155/2020/2545682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547346/
https://www.ncbi.nlm.nih.gov/pubmed/33061823
http://dx.doi.org/10.1155/2020/2545682

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