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GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies

After the first case of Coronavirus disease 2019 (COVID-19) was reported in Wuhan, COVID-19 has rapidly spread to almost all parts of world. Angiotensin converting enzyme 2 (ACE2) receptor can bind to spike protein of SARS-CoV-2. Then, the spike protein of SARS-CoV-2 can be cleaved and activated by...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Yuan, Lin, Yu-Shih, Yang, Yao-Hsu, Shu, Li-Hsin, Cheng, Yu-Ching, Liu, Hung Te
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547400/
https://www.ncbi.nlm.nih.gov/pubmed/33049583
http://dx.doi.org/10.1016/j.biopha.2020.110816