Cargando…

GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies

After the first case of Coronavirus disease 2019 (COVID-19) was reported in Wuhan, COVID-19 has rapidly spread to almost all parts of world. Angiotensin converting enzyme 2 (ACE2) receptor can bind to spike protein of SARS-CoV-2. Then, the spike protein of SARS-CoV-2 can be cleaved and activated by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ching-Yuan, Lin, Yu-Shih, Yang, Yao-Hsu, Shu, Li-Hsin, Cheng, Yu-Ching, Liu, Hung Te
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Masson SAS. 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547400/ https://www.ncbi.nlm.nih.gov/pubmed/33049583 http://dx.doi.org/10.1016/j.biopha.2020.110816

Ejemplares similares

GB-2 blocking the interaction between ACE2 and wild type and mutation of spike protein of SARS-CoV-2
por: Tsai, Ming-Shao, et al.
Publicado: (2021)

Anisomeles indica Extracts and Their Constituents Suppress the Protein Expression of ACE2 and TMPRSS2 In Vivo and In Vitro
por: Chen, Yu-Ru, et al.
Publicado: (2023)

Potential inhibitor for blocking binding between ACE2 and SARS-CoV-2 spike protein with mutations
por: Tsai, Ming-Shao, et al.
Publicado: (2022)

Potential Simultaneous Inhibitors of Angiotensin-Converting Enzyme 2 and Transmembrane Protease, Serine 2
por: Wu, Ching-Yuan, et al.
Publicado: (2020)

Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19
por: Li, Hsin-Hsien, et al.
Publicado: (2021)

Schizophyllum commune Reduces Expression of the SARS-CoV-2 Receptors ACE2 and TMPRSS2
por: Sun, Te-Kai, et al.
Publicado: (2022)

ACE inhibitors on ACE1, ACE2, and TMPRSS2 expression and spheroid attachment on human endometrial Ishikawa cells
por: Fernando, Sudini R., et al.
Publicado: (2022)

ACE2 and TMPRSS2 Expression in Hepatocytes of Chronic HBV Infection Patients
por: Hu, Xiao-Xiao, et al.
Publicado: (2021)

Sex, androgens and regulation of pulmonary AR, TMPRSS2 and ACE2
por: Baratchian, Mehdi, et al.
Publicado: (2020)

Soluble ACE2 and TMPRSS2 Levels in the Serum of Asthmatic Patients
por: Lee, Ji-Hyang, et al.
Publicado: (2022)

ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study
por: Gill, Dipender, et al.
Publicado: (2020)

Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2
por: Qiao, Yuanyuan, et al.
Publicado: (2021)

New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis
por: Hou, Yuan, et al.
Publicado: (2020)

Gastrointestinal cancers, ACE-2/TMPRSS2 expression and susceptibility to COVID-19
por: Shafiee, Sepehr, et al.
Publicado: (2021)

ACE2 and TMPRSS2 Immunolocalization and COVID-19-Related Thyroid Disorder
por: Park, Gi-Cheol, et al.
Publicado: (2022)

Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells
por: Kimura, Hiroki, et al.
Publicado: (2020)

Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein
por: Sagar, Satish, et al.
Publicado: (2021)

Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis
por: Ko, Chun-Jung, et al.
Publicado: (2020)

ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19
por: Dong, Mengzhen, et al.
Publicado: (2020)

ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review
por: Lechien, Jerome R., et al.
Publicado: (2020)

COVID-19 and the male susceptibility: the role of ACE2, TMPRSS2 and the androgen receptor
por: Mjaess, G., et al.
Publicado: (2020)

Malignancy going viral: ACE2 and TMPRSS2 expression in conjunctival neoplastic diseases
por: Grajewski, Rafael S., et al.
Publicado: (2021)

Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
por: Kermani, Nazanin Zounemat, et al.
Publicado: (2021)

Exposure to particulate matter upregulates ACE2 and TMPRSS2 expression in the murine lung()
por: Sagawa, Tomoya, et al.
Publicado: (2021)

Age and gender differences in ACE2 and TMPRSS2 expressions in oral epithelial cells
por: Peng, Jinfeng, et al.
Publicado: (2021)

ACE2 and TMPRSS2 in human saliva can adsorb to the oral mucosal epithelium
por: Zhu, Fucun, et al.
Publicado: (2021)

ACE2 and TMPRSS2 Potential Involvement in Genetic Susceptibility to SARS-COV-2 in Cancer Patients
por: Ravaioli, Sara, et al.
Publicado: (2020)

Expression of ACE2, the SARS-CoV-2 Receptor, and TMPRSS2 in Prostate Epithelial Cells
por: Song, Hanbing, et al.
Publicado: (2020)

Expression of ACE2, the SARS-CoV-2 receptor, and TMPRSS2 in prostate epithelial cells
por: Song, Hanbing, et al.
Publicado: (2020)

TMPRSS2: An Equally Important Protease as ACE2 in the Pathogenicity of SARS-CoV-2 Infection
por: Parmar, Malvinder S.
Publicado: (2021)

The Pursuit of COVID-19 Biomarkers: Putting the Spotlight on ACE2 and TMPRSS2 Regulatory Sequences
por: Barash, Ayelet, et al.
Publicado: (2020)

Correction to: Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma
por: Kermani, Nazanin Zounemat, et al.
Publicado: (2021)

Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19
por: SENAPATI, SABYASACHI, et al.
Publicado: (2021)

Association between ACE2 and TMPRSS2 nasopharyngeal expression and COVID-19 respiratory distress
por: Rossi, Átila Duque, et al.
Publicado: (2021)

ACE2 and TMPRSS2 SNPs as Determinants of Susceptibility to, and Severity of, a COVID-19 Infection
por: Abdelsattar, S., et al.
Publicado: (2022)

Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo
por: Lo, Yi-Ching, et al.
Publicado: (2012)

Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study
por: Chang, Geng-He, et al.
Publicado: (2022)

ACE/ACE2 Ratio and MMP-9 Activity as Potential Biomarkers in Tuberculous Pleural Effusions
por: Hsieh, Wen-Yeh, et al.
Publicado: (2012)

N-3 polyunsaturated fatty acids block the trimethylamine-N-oxide- ACE2- TMPRSS2 cascade to inhibit the infection of human endothelial progenitor cells by SARS-CoV-2
por: Chiang, En-Pei Isabel, et al.
Publicado: (2022)

Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory Tract
por: Liu, Yichuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3oglmdjn284vemn0tnef79fq7g