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Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8(+) T cell activation in fluorinated ethylene propylene cell culture bags

BACKGROUND: A major obstacle to anti-viral and -tumor cell vaccination and T cell immunotherapy is the ability to produce dendritic cells (DCs) in a suitable clinical setting. It is imperative to develop closed cell culture systems to accelerate the translation of promising DC-based cell therapy pro...

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Detalles Bibliográficos
Autores principales: Bastien, Jean-Philippe, Fekete, Natalie, Beland, Ariane V., Lachambre, Marie-Paule, Laforte, Veronique, Juncker, David, Dave, Vibhuti, Roy, Denis-Claude, Hoesli, Corinne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547414/
https://www.ncbi.nlm.nih.gov/pubmed/33036618
http://dx.doi.org/10.1186/s12967-020-02543-1