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The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

BACKGROUND: Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal insufficiency. Enhanced intracellular conversion of inactive cortisone to active...

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Detalles Bibliográficos
Autores principales: Dineen, Rosemary, Behan, Lucy-Ann, Kelleher, Grainne, Hannon, Mark J., Brady, Jennifer J., Rogers, Bairbre, Keevil, Brian G., Tormey, William, Smith, Diarmuid, Thompson, Christopher J., McKenna, Malachi J., Arlt, Wiebke, Stewart, Paul M., Agha, Amar, Sherlock, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547490/
https://www.ncbi.nlm.nih.gov/pubmed/33036588
http://dx.doi.org/10.1186/s12902-020-00633-1