Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings

INTRODUCTION: One method for assessing the in vitro response to CFTR‐modulating compounds is by analysis of epithelial monolayers in an Ussing chamber, where the apical and basolateral surfaces are isolated and the potential difference, short‐circuit current, and transepithelial resistance can be mo...

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Detalles Bibliográficos
Autores principales: Bratcher, Preston E., Yadav, Sangya, Shaughnessy, Ciaran A., Thornell, Ian M., Zeitlin, Pamela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547589/
https://www.ncbi.nlm.nih.gov/pubmed/33038073
http://dx.doi.org/10.14814/phy2.14603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547589/
https://www.ncbi.nlm.nih.gov/pubmed/33038073
http://dx.doi.org/10.14814/phy2.14603

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