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The mechanisms of hydroxychloroquine in rheumatoid arthritis treatment: Inhibition of dendritic cell functions via Toll like receptor 9 signaling

Hydroxychloroquine (HCQ) is one of the most commonly prescribed immune-suppressants in treating rheumatoid arthritis (RA). Our previous research showed that HCQ suppressed RA development by inhibiting T follicular helper (Tfh) cells directly. Dendritic cells (DCs) serve as the link between innate an...

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Detalles Bibliográficos
Autores principales: Han, Jiaochan, Li, Xing, Luo, Xiaoqing, He, Juan, Huang, Xuechan, Zhou, Qingyou, Han, Yanping, Jie, Hongyu, Zhuang, Jian, Li, Yehao, Yang, Fangyuan, Zhai, Zeqing, Wu, Shufan, He, Yi, Yang, Bin, Sun, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547638/
https://www.ncbi.nlm.nih.gov/pubmed/33049581
http://dx.doi.org/10.1016/j.biopha.2020.110848