Cargando…
Molecular dynamics of the histamine H3 membrane receptor reveals different mechanisms of GPCR signal transduction
In this work, we studied the mechanisms of classical activation and inactivation of signal transduction by the histamine H3 receptor, a 7-helix transmembrane bundle G-Protein Coupled Receptor through long-time-scale atomistic molecular dynamics simulations of the receptor embedded in a hydrated doub...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547658/ https://www.ncbi.nlm.nih.gov/pubmed/33037273 http://dx.doi.org/10.1038/s41598-020-73483-5 |