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FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer

Polyamine biosynthesis is an essential metabolic pathway for cell growth and differentiation in non-small-cell lung cancer (NSCLC). Fragile-site associated tumour suppressor (FATS) is a novel gene involved in cancer. The results of our previous study showed that FATS-mediated polyubiquitination of p...

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Detalles Bibliográficos
Autores principales: Qiu, Li, Hu, Linfei, Wang, Huijuan, Li, Jinling, Ruan, Xianhui, Sun, Bingsheng, Zhi, Jingtai, Zheng, Xiangqian, Gu, Lin, Gao, Ming, Kong, Pengzhou, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547721/
https://www.ncbi.nlm.nih.gov/pubmed/33037185
http://dx.doi.org/10.1038/s41419-020-03052-1