Dual-Acting Peripherally Restricted Delta/Kappa Opioid (CAV1001) Produces Antinociception in Animal Models of Sub-Acute and Chronic Pain

BACKGROUND: The development of highly efficacious alternatives to mu-opioid analgesics represents an urgent unmet medical and public health need. In the presence of inflammation both delta- and kappa-opioid agonists, acting on peripheral sensory neurons, mediate analgesia. The dual-acting, periphera...

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Detalles Bibliográficos
Autores principales: Hartrick, Craig T, Poulin, Dominic, Molenaar, Rebekka, Hartrick, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547792/
https://www.ncbi.nlm.nih.gov/pubmed/33116788
http://dx.doi.org/10.2147/JPR.S262303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547792/
https://www.ncbi.nlm.nih.gov/pubmed/33116788
http://dx.doi.org/10.2147/JPR.S262303

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