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Fibrotic scar after experimental autoimmune encephalomyelitis inhibits oligodendrocyte differentiation

Remyelination failure is a crucial component of disease progression in the autoimmune demyelinating disease Multiple Sclerosis (MS). The regenerative capacity of oligodendrocyte progenitor cells (OPCs) to replace myelinating oligodendrocytes is likely influenced by many aspects of the lesion environ...

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Detalles Bibliográficos
Autores principales: Yahn, Stephanie L., Li, Jiajun, Goo, Irene, Gao, Han, Brambilla, Roberta, Lee, Jae K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547849/
https://www.ncbi.nlm.nih.gov/pubmed/31731043
http://dx.doi.org/10.1016/j.nbd.2019.104674