Morphing of Amphipathic Helices to Explore the Activity and Selectivity of Membranolytic Antimicrobial Peptides

[Image: see text] Naturally occurring membranolytic antimicrobial peptides (AMPs) are rarely cell-type selective and highly potent at the same time. Template-based peptide design can be used to generate AMPs with improved properties de novo. Following this approach, 18 linear peptides were obtained...

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Detalles Bibliográficos
Autores principales: Müller, Alex T., Posselt, Gernot, Gabernet, Gisela, Neuhaus, Claudia, Bachler, Simon, Blatter, Markus, Pfeiffer, Bernhard, Hiss, Jan A., Dittrich, Petra S., Altmann, Karl-Heinz, Wessler, Silja, Schneider, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547863/
https://www.ncbi.nlm.nih.gov/pubmed/32936629
http://dx.doi.org/10.1021/acs.biochem.0c00565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547863/
https://www.ncbi.nlm.nih.gov/pubmed/32936629
http://dx.doi.org/10.1021/acs.biochem.0c00565

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