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Template-Directed Catalysis of a Multistep Reaction Pathway for Nonenzymatic RNA Primer Extension
[Image: see text] Before the advent of polymerase enzymes, the copying of genetic material during the origin of life may have involved the nonenzymatic polymerization of RNA monomers that are more reactive than the biological nucleoside triphosphates. Activated RNA monomers such as nucleotide 5′-pho...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547881/ https://www.ncbi.nlm.nih.gov/pubmed/30566332 http://dx.doi.org/10.1021/acs.biochem.8b01156 |