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Experimental and Computational Evidence for a Loose Transition State in Phosphoroimidazolide Hydrolysis
[Image: see text] Phosphoroimidazolides play a critical role in several enzymatic phosphoryl transfer reactions and have been studied extensively as activated monomers for nonenzymatic nucleic acid replication, but the detailed mechanisms of these phosphoryl transfer reactions remain elusive. Some a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547882/ https://www.ncbi.nlm.nih.gov/pubmed/26974265 http://dx.doi.org/10.1021/jacs.6b00784 |