Cargando…

High-Resolution Transcriptomic Profiling of the Heart During Chronic Stress Reveals Cellular Drivers of Cardiac Fibrosis and Hypertrophy

BACKGROUND: Cardiac fibrosis is a key antecedent to many types of cardiac dysfunction including heart failure. Physiological factors leading to cardiac fibrosis have been recognized for decades. However, the specific cellular and molecular mediators that drive cardiac fibrosis, and the relative effe...

Descripción completa

Detalles Bibliográficos
Autores principales: McLellan, Micheal A., Skelly, Daniel A., Dona, Malathi S.I., Squiers, Galen T., Farrugia, Gabriella E., Gaynor, Taylah L., Cohen, Charles D., Pandey, Raghav, Diep, Henry, Vinh, Antony, Rosenthal, Nadia A., Pinto, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547893/
https://www.ncbi.nlm.nih.gov/pubmed/32795101
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045115