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High-Resolution Transcriptomic Profiling of the Heart During Chronic Stress Reveals Cellular Drivers of Cardiac Fibrosis and Hypertrophy
BACKGROUND: Cardiac fibrosis is a key antecedent to many types of cardiac dysfunction including heart failure. Physiological factors leading to cardiac fibrosis have been recognized for decades. However, the specific cellular and molecular mediators that drive cardiac fibrosis, and the relative effe...
Autores principales: | McLellan, Micheal A., Skelly, Daniel A., Dona, Malathi S.I., Squiers, Galen T., Farrugia, Gabriella E., Gaynor, Taylah L., Cohen, Charles D., Pandey, Raghav, Diep, Henry, Vinh, Antony, Rosenthal, Nadia A., Pinto, Alexander R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547893/ https://www.ncbi.nlm.nih.gov/pubmed/32795101 http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045115 |
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