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A Phase I Placebo-Controlled Trial Comparing the Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration on Respiratory Drive

INTRODUCTION: Buprenorphine is a partial μ-opioid receptor agonist that, unlike full μ-opioid receptor agonists, has been shown to have a ceiling effect on respiratory depression. Buprenorphine buccal film (BBF) is approved by the US Food and Drug Administration for use in patients with chronic pain...

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Detalles Bibliográficos
Autores principales: Webster, Lynn R., Hansen, Erik, Cater, Jacqueline, Smith, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547962/
https://www.ncbi.nlm.nih.gov/pubmed/32978722
http://dx.doi.org/10.1007/s12325-020-01481-0