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A Phase I Placebo-Controlled Trial Comparing the Effects of Buprenorphine Buccal Film and Oral Oxycodone Hydrochloride Administration on Respiratory Drive
INTRODUCTION: Buprenorphine is a partial μ-opioid receptor agonist that, unlike full μ-opioid receptor agonists, has been shown to have a ceiling effect on respiratory depression. Buprenorphine buccal film (BBF) is approved by the US Food and Drug Administration for use in patients with chronic pain...
Autores principales: | Webster, Lynn R., Hansen, Erik, Cater, Jacqueline, Smith, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547962/ https://www.ncbi.nlm.nih.gov/pubmed/32978722 http://dx.doi.org/10.1007/s12325-020-01481-0 |
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