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Bioequivalence Study Comparing Fixed-Dose Combination of Clopidogrel and Aspirin with Coadministration of Individual Formulations in Chinese Subjects Under Fed Conditions: A Phase I, Open-Label, Randomized, Crossover Study

INTRODUCTION: Simultaneous administration of acetylsalicylic acid (ASA) and clopidogrel has demonstrated efficacy in the treatment of acute coronary syndrome. Clopidogrel + ASA in a fixed-dose combination (FDC) provides a pharmaceutical option to enhance adherence to the coadministration of dual ant...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ming, Jeffrey E., Kong, Fangyuan, Yin, Huiqiu, Zhang, Linlin, Bai, Haihong, Liu, Huijuan, Qi, Lu, Wang, Yu, Xie, Fang, Yang, Na, Ping, Chuan, Li, Yi, Chen, Liu, Han, Chunyu, Liu, Ju, Wang, Xinghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547973/
https://www.ncbi.nlm.nih.gov/pubmed/32970315
http://dx.doi.org/10.1007/s12325-020-01486-9