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Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation

Although endometrial cancer is the most common cancer of the female reproductive tract, we have little understanding of what controls endometrial cancer beyond the transcriptional effects of steroid hormones such as estrogen. As a result, we have limited therapeutic options for the ~62,000 women dia...

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Detalles Bibliográficos
Autores principales: Popli, Pooja, Richters, Megan M., Chadchan, Sangappa B., Kim, Tae Hoon, Tycksen, Eric, Griffith, Obi, Thaker, Premal H., Griffith, Malachi, Kommagani, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548007/
https://www.ncbi.nlm.nih.gov/pubmed/33040078
http://dx.doi.org/10.1038/s41419-020-03055-y