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Itaconic acid hybrids as potential anticancer agents

ABSTRACT: In this paper, we report the synthesis of novel hybrids 2–14 based on itaconic acid and fluoroaniline, pyridine, indole and quinoline scaffolds. Itaconic acid is a naturally occurring compound with a Michael acceptor moiety, a key structural feature in several anticancer and antiviral drug...

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Detalles Bibliográficos
Autores principales: Perković, Ivana, Beus, Maja, Schols, Dominique, Persoons, Leentje, Zorc, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548052/
https://www.ncbi.nlm.nih.gov/pubmed/33043404
http://dx.doi.org/10.1007/s11030-020-10147-6