Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes

Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient leukocyte capture and rolling. We demonstrate that...

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Detalles Bibliográficos
Autores principales: Mylvaganam, Sivakami, Riedl, Magdalena, Vega, Anthony, Collins, Richard F., Jaqaman, Khuloud, Grinstein, Sergio, Freeman, Spencer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548125/
https://www.ncbi.nlm.nih.gov/pubmed/32579925
http://dx.doi.org/10.1016/j.celrep.2020.107798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548125/
https://www.ncbi.nlm.nih.gov/pubmed/32579925
http://dx.doi.org/10.1016/j.celrep.2020.107798

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