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Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes
Multivalent complexes of endothelial adhesion receptors (e.g., selectins) engage leukocytes to orchestrate their migration to inflamed tissues. Proper anchorage and sufficient density (clustering) of endothelial receptors are required for efficient leukocyte capture and rolling. We demonstrate that...
Autores principales: | Mylvaganam, Sivakami, Riedl, Magdalena, Vega, Anthony, Collins, Richard F., Jaqaman, Khuloud, Grinstein, Sergio, Freeman, Spencer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548125/ https://www.ncbi.nlm.nih.gov/pubmed/32579925 http://dx.doi.org/10.1016/j.celrep.2020.107798 |
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