Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26

Related research has recognized the vital role of methionine cycle metabolism in cancers. However, the role and mechanism of methionine cycle metabolism in hepatocellular carcinoma are still unknown. In this study, we found that [Cu(ttpy-tpp)Br(2)]Br (Referred to as CTB) could induce hepatocellular...

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Detalles Bibliográficos
Autores principales: Jin, Chun, Li, Yujia, Su, Ying, Guo, Zijian, Wang, Xiaoyong, Wang, Shijun, Zhang, Feng, Zhang, Zili, Shao, Jiangjuan, Zheng, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548283/
https://www.ncbi.nlm.nih.gov/pubmed/33041323
http://dx.doi.org/10.1038/s41419-020-03048-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548283/
https://www.ncbi.nlm.nih.gov/pubmed/33041323
http://dx.doi.org/10.1038/s41419-020-03048-x

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