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Disrupted Coordination of Hypoglossal Motor Control in a Mouse Model of Pediatric Dysphagia in DiGeorge/22q11.2 Deletion Syndrome

We asked whether the physiological and morphologic properties of hypoglossal motor neurons (CNXII MNs) that innervate protruder or retractor tongue muscles are disrupted in neonatal LgDel mice that carry a heterozygous deletion parallel to that associated with DiGeorge/22q11.2 deletion syndrome (22q...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Popratiloff, Anastas, Motahari, Zahra, LaMantia, Anthony-Samuel, Mendelowitz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548433/
https://www.ncbi.nlm.nih.gov/pubmed/32855199
http://dx.doi.org/10.1523/ENEURO.0520-19.2020