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Down-regulation of COX-2 activity by 1α,25(OH)(2)D(3) is VDR dependent in endothelial cells transformed by Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor
Our previous reports showed that 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) has antiproliferative actions in endothelial cells stably expressing viral G protein-coupled receptor (vGPCR) associated with the pathogenesis of Kaposi's sarcoma. It has been reported that COX-2 enzyme, involved in...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549067/ https://www.ncbi.nlm.nih.gov/pubmed/33072916 http://dx.doi.org/10.1016/j.heliyon.2020.e05149 |