Down-regulation of COX-2 activity by 1α,25(OH)(2)D(3) is VDR dependent in endothelial cells transformed by Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

Our previous reports showed that 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) has antiproliferative actions in endothelial cells stably expressing viral G protein-coupled receptor (vGPCR) associated with the pathogenesis of Kaposi's sarcoma. It has been reported that COX-2 enzyme, involved in...

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Detalles Bibliográficos
Autores principales: Tapia, Cinthya, Zamarreño, Fernando, Salvador, Gabriela Alejandra, Casali, Cecilia Irene, Viso, Juan, Fernandez, María del Carmen, White, John H., González-Pardo, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549067/
https://www.ncbi.nlm.nih.gov/pubmed/33072916
http://dx.doi.org/10.1016/j.heliyon.2020.e05149

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