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Diverse Cell Stimulation Kinetics Identify Predictive Signal Transduction Models

Computationally understanding the molecular mechanisms that give rise to cell signaling responses upon different environmental, chemical, and genetic perturbations is a long-standing challenge that requires models that fit and predict quantitative responses for new biological conditions. Overcoming...

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Detalles Bibliográficos
Autores principales: Jashnsaz, Hossein, Fox, Zachary R., Hughes, Jason J., Li, Guoliang, Munsky, Brian, Neuert, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549069/
https://www.ncbi.nlm.nih.gov/pubmed/33083733
http://dx.doi.org/10.1016/j.isci.2020.101565