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A radiolabeled drug tracing method to study neurotrophin-3 retention and distribution in the cochlea after nano-based local delivery

Hearing loss is the most common sensory deficit worldwide with no approved therapeutics for treatment. Local neurotrophin delivery into the cochlea has shown great potential in protecting and repairing the sensory cells important for hearing. However, delivery of these factors into the inner ear at...

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Detalles Bibliográficos
Autores principales: Lam, Patrick, Gunewardene, Niliksha, Ma, Yutian, Caruso, Frank, Nguyen, Trung, Flynn, Brianna, Wise, Andrew K., Richardson, Rachael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549113/
https://www.ncbi.nlm.nih.gov/pubmed/33072529
http://dx.doi.org/10.1016/j.mex.2020.101078