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Lipid Droplets Maintain Energy Homeostasis and Glioblastoma Growth via Autophagic Release of Stored Fatty Acids

Recently, lipid metabolism reprogramming has been further evidenced in malignancies via the observation of large amounts of lipid droplets (LDs) in human tumors, including in glioblastoma (GBM), the most lethal primary brain tumor. However, the role played by LDs in tumor cells remains unknown. Here...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoning, Geng, Feng, Cheng, Xiang, Guo, Qiang, Zhong, Yaogang, Cloughesy, Timothy F., Yong, William H., Chakravarti, Arnab, Guo, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549116/
https://www.ncbi.nlm.nih.gov/pubmed/33083736
http://dx.doi.org/10.1016/j.isci.2020.101569