Characterization of cell fate probabilities in single-cell data with Palantir

Single-cell RNA sequencing (scRNA-seq) studies of differentiating systems have raised fundamental questions regarding the discrete versus continuous nature of both differentiation and cell fate. Here we present Palantir, an algorithm that models trajectories of differentiating cells—treating cell fa...

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Detalles Bibliográficos
Autores principales: Setty, Manu, Kiseliovas, Vaidotas, Levine, Jacob, Gayoso, Adam, Mazutis, Linas, Pe’er, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549125/
https://www.ncbi.nlm.nih.gov/pubmed/30899105
http://dx.doi.org/10.1038/s41587-019-0068-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549125/
https://www.ncbi.nlm.nih.gov/pubmed/30899105
http://dx.doi.org/10.1038/s41587-019-0068-4

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