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Characterization of cell fate probabilities in single-cell data with Palantir
Single-cell RNA sequencing (scRNA-seq) studies of differentiating systems have raised fundamental questions regarding the discrete versus continuous nature of both differentiation and cell fate. Here we present Palantir, an algorithm that models trajectories of differentiating cells—treating cell fa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549125/ https://www.ncbi.nlm.nih.gov/pubmed/30899105 http://dx.doi.org/10.1038/s41587-019-0068-4 |