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Maternal obesity causes fetal hypothalamic insulin resistance and disrupts development of hypothalamic feeding pathways

OBJECTIVE: Perinatal exposure to maternal obesity results in predisposition of offspring to develop obesity later in life. Increased weight gain in offspring exposed to maternal obesity is usually associated with hyperphagia, implicating altered central regulation of food intake as a cause. We aimed...

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Detalles Bibliográficos
Autores principales: Dearden, L, Buller, S, Furigo, IC, Fernandez-Twinn, D.S., Ozanne, SE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549144/
https://www.ncbi.nlm.nih.gov/pubmed/32919096
http://dx.doi.org/10.1016/j.molmet.2020.101079