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Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways

BACKGROUND: Trophoblast cells are required for the establishment of pregnancy and fetal development. Apoptosis is an essential feature for trophoblast invasion. Uncontrolled trophoblast apoptosis is related to some complicate pregnancies. Oxidative stress (OS) is an important inducer of trophoblast...

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Detalles Bibliográficos
Autores principales: He, Bin, Li, Qi Yue, Wu, Yuan Yuan, Ruan, Jing Ling, Teng, Xiao Ming, Li, Da Jin, Tang, Chuan Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549196/
https://www.ncbi.nlm.nih.gov/pubmed/33046085
http://dx.doi.org/10.1186/s12958-020-00658-0