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MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca(2+) channels and PIP(2)
Phosphatidylinositol 4,5-bisphosphate (PIP(2)) acts as substrate and unmodified ligand for Gq-protein-coupled receptor signalling in vascular smooth muscle cells (VSMCs) that is central for initiating contractility. The present work investigated how PIP(2) might perform these two potentially conflic...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549404/ https://www.ncbi.nlm.nih.gov/pubmed/32707323 http://dx.doi.org/10.1016/j.vph.2020.106776 |