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MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca(2+) channels and PIP(2)

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) acts as substrate and unmodified ligand for Gq-protein-coupled receptor signalling in vascular smooth muscle cells (VSMCs) that is central for initiating contractility. The present work investigated how PIP(2) might perform these two potentially conflic...

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Detalles Bibliográficos
Autores principales:	Jahan, Kazi S., Shi, Jian, Greenberg, Harry Z.E., Khavandi, Sam, Baudel, Miguel Martín-Aragón, Barrese, Vincenzo, Greenwood, Iain A., Albert, Anthony P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549404/ https://www.ncbi.nlm.nih.gov/pubmed/32707323 http://dx.doi.org/10.1016/j.vph.2020.106776

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