Etoposide Amorphous Nanopowder for Improved Oral Bioavailability: Formulation Development, Optimization, in vitro and in vivo Evaluation

INTRODUCTION: Etoposide refers to a derivative of podophyllotoxin, which plays an important role in the treatment of cancer due to its prominent anti-tumor effect. As a BCS IV drug, etoposide exhibits insufficient aqueous solubility and permeability, thereby limiting its oral absorption. To enhance...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yue, Wang, Shuhang, Xu, Yingju, Wang, Ping, Li, Sukai, Liu, Lu, Liu, Mengyan, Jin, Xiangqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549503/
https://www.ncbi.nlm.nih.gov/pubmed/33116490
http://dx.doi.org/10.2147/IJN.S265817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549503/
https://www.ncbi.nlm.nih.gov/pubmed/33116490
http://dx.doi.org/10.2147/IJN.S265817

Ejemplares similares