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Etoposide Amorphous Nanopowder for Improved Oral Bioavailability: Formulation Development, Optimization, in vitro and in vivo Evaluation

INTRODUCTION: Etoposide refers to a derivative of podophyllotoxin, which plays an important role in the treatment of cancer due to its prominent anti-tumor effect. As a BCS IV drug, etoposide exhibits insufficient aqueous solubility and permeability, thereby limiting its oral absorption. To enhance...

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Detalles Bibliográficos
Autores principales:	Wang, Yue, Wang, Shuhang, Xu, Yingju, Wang, Ping, Li, Sukai, Liu, Lu, Liu, Mengyan, Jin, Xiangqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549503/ https://www.ncbi.nlm.nih.gov/pubmed/33116490 http://dx.doi.org/10.2147/IJN.S265817

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