Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes

BACKGROUND: Repressor element 1‐silencing transcription factor (REST) acts as a transcriptional repressor by recruiting several chromatin modifiers, including histone deacetylase (HDAC). Elevated REST expression in medulloblastoma has been associated with tumor progression nevertheless, the tumor sh...

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Detalles Bibliográficos
Autores principales: Alshawli, Abdulelah S., Wurdak, Heiko, Wood, Ian C., Ladbury, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549561/
https://www.ncbi.nlm.nih.gov/pubmed/32720471
http://dx.doi.org/10.1002/mgg3.1429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549561/
https://www.ncbi.nlm.nih.gov/pubmed/32720471
http://dx.doi.org/10.1002/mgg3.1429

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