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Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes
BACKGROUND: Repressor element 1‐silencing transcription factor (REST) acts as a transcriptional repressor by recruiting several chromatin modifiers, including histone deacetylase (HDAC). Elevated REST expression in medulloblastoma has been associated with tumor progression nevertheless, the tumor sh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549561/ https://www.ncbi.nlm.nih.gov/pubmed/32720471 http://dx.doi.org/10.1002/mgg3.1429 |