Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta

INTRODUCTION: Severe hypoxia exists in placentas during early pregnancy, with reoxygenation during mid-gestation. Hypoxia-inducible factor-1α (Hif1α), an oxygen sensor, initiates placental vascular development. We have shown that the placental vasculature in Hmox1-deficient (Hmox1(+/−), Het) pregnan...

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Detalles Bibliográficos
Autores principales: Zhao, Hui, Narasimhan, Purnima, Kalish, Flora, Wong, Ronald J., Stevenson, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Classics Revisited
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549641/
https://www.ncbi.nlm.nih.gov/pubmed/32784053
http://dx.doi.org/10.1016/j.placenta.2020.07.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549641/
https://www.ncbi.nlm.nih.gov/pubmed/32784053
http://dx.doi.org/10.1016/j.placenta.2020.07.015

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