Multiple Rap1 effectors control Epac1-mediated tightening of endothelial junctions

Epac1 and Rap1 mediate cAMP-induced tightening of endothelial junctions. We have previously found that one of the mechanisms is the inhibition of Rho-mediated tension in radial stress fibers by recruiting the RhoGAP ArhGAP29 in a complex containing the Rap1 effectors Rasip1 and Radil. However, other...

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Detalles Bibliográficos
Autores principales: Pannekoek, Willem-Jan, Vliem, Marjolein J., Bos, Johannes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper/Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549671/
https://www.ncbi.nlm.nih.gov/pubmed/29388865
http://dx.doi.org/10.1080/21541248.2018.1431512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549671/
https://www.ncbi.nlm.nih.gov/pubmed/29388865
http://dx.doi.org/10.1080/21541248.2018.1431512

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