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Multiple Rap1 effectors control Epac1-mediated tightening of endothelial junctions
Epac1 and Rap1 mediate cAMP-induced tightening of endothelial junctions. We have previously found that one of the mechanisms is the inhibition of Rho-mediated tension in radial stress fibers by recruiting the RhoGAP ArhGAP29 in a complex containing the Rap1 effectors Rasip1 and Radil. However, other...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549671/ https://www.ncbi.nlm.nih.gov/pubmed/29388865 http://dx.doi.org/10.1080/21541248.2018.1431512 |