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Predicting RNA SHAPE scores with deep learning

Secondary structure prediction approaches rely typically on models of equilibrium free energies that are themselves based on in vitro physical chemistry. Recent transcriptome-wide experiments of in vivo RNA structure based on SHAPE-MaP experiments provide important information that may make it possi...

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Detalles Bibliográficos
Autores principales: Bliss, Noah, Bindewald, Eckart, Shapiro, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549691/
https://www.ncbi.nlm.nih.gov/pubmed/32476596
http://dx.doi.org/10.1080/15476286.2020.1760534