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Deficiency of the Tbc1d21 gene causes male infertility with morphological abnormalities of the sperm mitochondria and flagellum in mice

Approximately 2–15% of couples experience infertility, and around half of these cases are attributed to male infertility. We previously identified TBC1D21 as a sterility-related RabGAP gene derived from infertile men. However, the in vivo function of TBC1D21 in male fertility remains unclear. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Yun, Ke, Chih-Chun, Chen, Yen-Lin, Lin, Yu-Hua, Yu, I-Shing, Ku, Wei-Chi, O’Bryan, Moira K., Lin, Ying-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549768/
https://www.ncbi.nlm.nih.gov/pubmed/32976492
http://dx.doi.org/10.1371/journal.pgen.1009020