Kahweol activates the Nrf2/HO-1 pathway by decreasing Keap1 expression independently of p62 and autophagy pathways

Kahweol is a diterpene found in coffee beans and unfiltered coffee drinks. Several studies have demonstrated that kahweol induces the nuclear factor erythroid-2 related factor 2/ hemeoxygenase-1 (Nrf2/HO-1) pathway; however, the mechanisms involved are currently unknown. Kelch-like ECH-associated pr...

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Detalles Bibliográficos
Autores principales: Seo, Hye-Young, Lee, So-Hee, Lee, Ji-Ha, Hwang, Jae Seok, Kim, Mi Kyung, Jang, Byoung Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549774/
https://www.ncbi.nlm.nih.gov/pubmed/33044988
http://dx.doi.org/10.1371/journal.pone.0240478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549774/
https://www.ncbi.nlm.nih.gov/pubmed/33044988
http://dx.doi.org/10.1371/journal.pone.0240478

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