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Controlled release of ciprofloxacin and ceftriaxone from a single ototopical administration of antibiotic-loaded polymer microspheres and thermoresponsive gel

Acute otitis media (AOM) is the main indication for pediatric antibiotic prescriptions, accounting for 25% of prescriptions. While the use of topical drops can minimize the administered dose of antibiotic and adverse systemic effects compared to oral antibiotics, their use has limitations, partially...

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Detalles Bibliográficos
Autores principales: Bruk, Liza A., Dunkelberger, Katherine E., Khampang, Pawjai, Hong, Wenzhou, Sadagopan, Srivatsun, Alper, Cuneyt M., Fedorchak, Morgan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549778/
https://www.ncbi.nlm.nih.gov/pubmed/33045028
http://dx.doi.org/10.1371/journal.pone.0240535