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Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak

In genome evolution, genetic variants are the source of diversity, which natural selection acts upon. Treatment of human tuberculosis (TB) induces a strong selection pressure for the emergence of antibiotic resistance-conferring variants in the infecting Mycobacterium tuberculosis (MTB) strains. MTB...

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Detalles Bibliográficos
Autores principales: Godfroid, Maxime, Dagan, Tal, Merker, Matthias, Kohl, Thomas A., Diel, Roland, Maurer, Florian P., Niemann, Stefan, Kupczok, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549793/
https://www.ncbi.nlm.nih.gov/pubmed/32997707
http://dx.doi.org/10.1371/journal.ppat.1008357