Cargando…
Quantifying the probability of pharmacological success to inform compound progression decisions
The Probability of Pharmacology Success, or PoPS, is a powerful metric to inform progression decisions by quantifying a compound’s overall pharmacological strength based on its mechanism. It is defined as the probability that X level of pharmacology is achieved in Y proportion of patients at a safe...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7549803/ https://www.ncbi.nlm.nih.gov/pubmed/33045007 http://dx.doi.org/10.1371/journal.pone.0240234 |